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The different topics developed at the Institute of Organic and Analytical Chemistry (ICOA) are directed towards the design, synthesis and analysis of small molecules likely to have biological activities.

The institute is a Mixed Research Unit (UMR 7311) of the University of Orleans and the French National Center for Scientific Research (CNRS).

ICOA is also a member of:

and is a corresponding lab of French Alternative Energies and Atomic Energy Commission (CEA) LRC M09.

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Our latest 3 publications

Ayari, G. ; Kadhirvel, P. ; Favetta, P. ; Plano, B. ; Dejous, C. ; Carbonnier, B. ; Agrofoglio, L. A.
Synthesis of imprinted hydrogel microbeads by inverse Pickering emulsion to controlled release of adenosine 5′‑monophosphate
Materials Science and Engineering: C 2019, 101, 254-263.

Diharce, J. ; Cueto, M. ; Beltramo, M. ; Aucagne, V. ; Bonnet, P.
In silico peptide ligation: iterative residue docking and linking as a new approach to predict protein-peptide interactions
Molecules 2019, 24, 1351.

Sukach, V. A. ; Melnykov, S. ; Bertho S. ; Diachenko, I. V. ; Retailleau, P. ; Vovk, M. V. ; Gillaizeau, I.
Access to unprotected β-fluoroalkyl β-amino acids and their α-hydroxy derivatives
Org. Lett. 2019, 21, 2340–2345.

Our latest 2 patents

  1. Routier, S. ; Buron, F. ; Rodrigues, N. ; Fourrière-Grandclaude, G. ; Vandier, C. ; Chantome, A. ; Potier-Cartereaux, M. ; Gueguinou, M. ; Marionneau-Lambot, S.
    Ion channel inhibitor compounds for cancer treatment
  2. Patent N° Kind Date Application N° Date
    WO 2018215557 A1 29 Nov. 2018 WO 2018-EP63543 23 May 2018
    FR 3066761 A1 30 Nov. 2018 FR 2017-54564 23 May 2017

        Priority Application
                      FR 2017-54564 A 23 May 2017
        ref. chem. Abstract : 2018:2337629

  3. Svetlana, V. E. ; Suzenet, F. ; Routier, S. ; Ben Othman, R. ; Collet, A. ; Ivana, M. ; Delatouche, R. ; Petoud, S.
    Lanthanide complexes comprising derivatives of triethylenetetramine-​N,​N,​N',​N'',​N''',​N'''-​hexaacetic acid
  4. Patent N° Kind Date Application N° Date
    WO 2018130545 A1 19 Jul. 2018 WO 2018-EP50517 10 Jan. 2018
    FR 3061713 A1 13 Jul. 2018 FR 2017-50240 11 Jan. 2017

        Priority Application
                      FR 2017-50240 A Jan 11, 2017
        ref. chem. Abstract : 2018:1336212